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The best days  to conceive
Assisted Reproduction Center

The best days to conceive

The best days to conceive are the 3 to 4 days before ovulation, the day of ovulation, and the following day, determined with cycle tracking, ultrasound, or tests.

Planning a pregnancy is an important and responsible step in the life of each couple. Once all necessary examinations are completed and folic acid intake has begun, the next step is to understand how to correctly identify the most fertile days. This process requires not only knowledge of female physiology but also careful attention to detail, as even slight deviations can influence the chances of conception.

The phases of the menstrual cycle

The first day of the menstrual cycle is the first day of bleeding. The cycle consists of several phases, each playing a role in preparing the woman's body for potential conception. Understanding these processes is essential to accurately determine the "fertility window."

Follicular phase

During this period, the woman's body actively prepares for potential pregnancy. The dominant follicle develops, gradually enlarges, and becomes the environment for a maturing ovum. Simultaneously, blood estrogen levels increase, stimulating the thickening of the endometrium, creating favorable conditions for future embryo implantation. During this phase, the nature of vaginal secretions also changes: they become more transparent and viscous, aiding sperm movement through the genital tract. This phase can last from 7 to 21 days, depending on the individual characteristics of the woman.

Ovulatory phase

This phase is the shortest: it only lasts 12 to 24 hours. When the dominant follicle ruptures, the ovum is released: this is ovulation. If the ovum does not encounter sperm within 24 hours, it loses its fertilization capacity. It is important to note that this process is essential for conception, and couples wishing to have a child should focus on this exact moment. Ovulation symptoms can include minor lower abdominal pain, changes in vaginal discharge, increased libido, and sometimes a slight rise in basal body temperature.

Luteal phase

After ovulation, two scenarios are possible:

· If the ovum is fertilized, the embryo begins its journey through the fallopian tube, reaches the uterine cavity, and implants into the endometrium. The corpus luteum, which forms at the site where the follicle ruptured, actively produces progesterone, a hormone necessary to sustain pregnancy. Its level continues to rise, creating optimal conditions for embryo development.

· If fertilization does not occur, the ovum dies, the endometrium gradually thins, progesterone levels decrease, and menstruation begins. This cycle ends, and the body starts preparing again for potential pregnancy.

Determining the day of ovulation

The duration of the menstrual cycle varies from woman to woman and can normally range from 21 to 35 days. The luteal phase typically lasts about 14 days, so by subtracting this from the total cycle length, one can estimate the approximate day of ovulation. However, given individual differences, it is preferable to use more precise methods: folliculometry ultrasound, which monitors follicle growth in real time, or a blood test for progesterone levels, which only begins active synthesis after ovulation. There are also at-home ovulation tests based on measuring the luteinizing hormone level in urine.

The most fertile days for conception

Understanding the phases of the cycle helps identify the most fertile days. Since sperm can retain their fertilizing ability for up to 3-4 days and the ovum is viable for about 24 hours, conception most often occurs when intercourse takes place a few days before ovulation or on the day of ovulation. That is why doctors recommend regular sexual activity during this period to increase the chances of success.

The most favorable time for conception is 3 to 4 days before ovulation, the day of ovulation, and the following day. After this period, it is advisable to adopt a calmer lifestyle, as the process of embryo traveling to the uterus and implantation begins within the woman's body. At this stage, it is also helpful to avoid intense physical activity and stress, as they can negatively affect reproductive function.

What are the most fertile days within an IVF protocol?

In assisted reproduction techniques, the approach to determining the most fertile days differs from that of a natural cycle. In the case of IVF (in vitro fertilization), synchronizing the ovarian stimulation, oocyte retrieval, and embryo transfer steps is essential. Here, it is not so much the timing of natural ovulation that matters, but rather the reproductive specialist's work, who, under ultrasound and hormonal control, determines the day of the retrieval and the embryo transfer into the uterine cavity.

In the case of IVF with egg donation, the most important factor is not the day of natural ovulation but the preparation of the recipient's endometrium. Donated eggs are fertilized by sperm, and embryos are transferred into the uterus when the endometrium reaches optimal thickness and structure for implantation. Therefore, in these protocols, the most fertile days are precisely the embryo transfer days, which are scheduled by the doctor.

In the case of IVF with double donation (using donor eggs and sperm), the approach is similar: doctors synchronize the embryo development process with the status of the recipient woman's endometrium. The optimal day for transfer is chosen individually to maximize the chances of embryo implantation.

Thus, in IVF programs and donor protocols, the "most fertile days" are not determined by the physiological phases of the natural cycle but by medical protocols and professional decisions of the clinic's specialists.

If pregnancy does not occur

It is important to remember that pregnancy does not always occur immediately, even if all conditions are met. The probability of conception for a healthy couple within a cycle is only about 10 to 11%. Sometimes ovulation may be absent, and some cycles may be interrupted due to functional cysts or other individual factors of the body. That is why specialists recommend staying calm, not fixating on the result, and continuing planning.

If a woman is under 35, it is recommended to actively plan pregnancy for a year, and if over 35, for 6 months. If no result is achieved within these time frames, it is necessary to consult a reproductive specialist. A consultation can identify or exclude factors hindering conception, such as hormonal disorders, ovulation issues, or male infertility. Modern reproductive medicine offers many solutions, from medication correction to assisted reproductive techniques like IVF.

The final opinion

Understanding the phases of the menstrual cycle, monitoring ovulation, and properly planning your intimate life significantly increase the chances of conception. The key is to remain patient, trust your doctor, and remember that even if pregnancy does not occur immediately, it does not always indicate serious health problems. Natuvitro reproductive medicine clinic adheres to the highest quality standards, uses modern protocols, and adopts an individualized approach for each patient, helping couples realize their long-awaited dream of having a child.

Dr. Iñaki González-Foruria
Medical Director
Dr. Clàudia Forteza
Gynecologist specialized in assisted reproduction
Dr. Rebeca Beguería
Gynecologist specialized in assisted reproduction
Joan Massó
IVF Lab Director
Dr. Manel Fabó
Anaesthetist Doctor
Monica Mandas
Nursing
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