Modern IVF techniques: a step towards the future of reproductive medicine

Advanced techniques of in vitro fertilization (IVF) allow for pregnancy even in the most difficult clinical cases. Thanks to the rapid evolution of reproductive medicine, doctors can offer effective solutions to numerous IVF failures, poor quality of reproductive cells, genetic risks, and physiological problems that cannot be surgically corrected.

Innovative IVF Technologies

Modern IVF technologies can overcome even severe forms of infertility. The most effective techniques, widely used in clinical practice today, are presented below.

ICSI - Intracytoplasmic Sperm Injection

The ICSI method involves injecting a sperm cell directly into the cytoplasm of the egg using a micromanipulator. The procedure is carried out under the control of a high-precision microscope and is primarily used in cases of pronounced male infertility.

IMSI - Intracytoplasmic Injection of Morphologically Normal Sperm

IMSI is an improved form of ICSI. The main difference lies in the careful selection of sperm using a microscope with magnification up to 6,000 times. This allows for the selection of the most morphologically complete cells, which improves fertilization quality and the subsequent development of the embryo.

Assisted Hatching

This method is recommended for patients whose IVF attempts have repeatedly failed, as well as for women over 40 years old. The essence of the procedure is to create micro-incisions on the blastocyst's envelope, most often using a laser. This facilitates the hatching process and improves the likelihood of implantation in the uterine endometrium.

PGD - Preimplantation Genetic Diagnosis of Embryos

PGD allows for the detection of genetic and chromosomal abnormalities even before the embryo is transferred to the uterine cavity. This method is particularly useful for couples who:

• have been diagnosed with hereditary diseases;
• present structural or numerical chromosomal abnormalities;
• have undergone several unsuccessful IVF attempts;
• whose female partner is over 40 years old.

The diagnosis is safe for the embryo and allows for the selection of the most promising embryo in terms of implantation and normal further development.

GIFT and ZIFT - Transfer to the Fallopian Tubes

The GIFT and ZIFT techniques are based on the hypothesis that during the first two days following fertilization, the embryo develops better in the natural environment of the fallopian tubes.

• GIFT (Gamete Intrafallopian Transfer) - an egg and a sperm are inserted into the fallopian tube where fertilization occurs naturally.
• ZIFT (Zygote Intrafallopian Transfer) - a fertilized zygote is transferred to the fallopian tube 24 hours after in vitro fertilization.

Both procedures are performed under anesthesia and are only used if at least one fallopian tube is patent.

How to Choose an IVF Method?

The choice of technology depends on the causes of infertility, the age of the patient, the quality of the reproductive cells, and other individual factors. You can determine the best treatment strategy during a consultation with a specialist in this field.

You can obtain detailed information about IVF possibilities and choose an appropriate technique during an appointment with a specialist at the Natuvitro clinic.