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August: 9:00 - 18:00, Mon - Thu
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IVF for endometrial hyperplasia
Assisted Reproduction Center

IVF for endometrial hyperplasia

Endometrial hyperplasia is an abnormal increase in the thickness of the endometrium, the inner layer of the uterus. This condition is due to a proliferation of tissues, which can significantly affect a woman's reproductive potential, especially in the context of IVF (in vitro fertilization). Below, we will examine the main symptoms of endometrial hyperplasia, the treatment methods for endometrial hyperplasia, and the possibility of undergoing IVF in cases of endometrial hyperplasia.

Symptoms of Endometrial Hyperplasia

Endometrial hyperplasia can manifest with different symptoms, which depend on the degree of tissue proliferation and the individual characteristics of each woman. The most common symptoms are as follows:

  • Irregular menstruation: changes in the duration of the menstrual cycle, bleeding between cycles, very heavy periods.
     
  • Pain in the lower abdomen, pressure in the pelvic region.
     
  • Bleeding after menopause should be considered a potential symptom of endometrial hyperplasia.
     
  • Fatigue and weakness: constant blood loss can lead to anemia.

Causes of Endometrial Hyperplasia

Endometrial hyperplasia is generally caused by hormonal disorders, particularly an imbalance between estrogen and progesterone. The main causes are as follows:

  1. Excess estrogen: estrogens stimulate the growth of the endometrium, and an excess of estrogen without the support of progesterone can lead to hyperplasia. 
     
  2. Polycystic ovary syndrome (PCOS): PCOS can lead to menstrual irregularities and excessive estrogen production.
     
  3. Obesity: fat cells produce estrogens, which can lead to excess estrogen in the body.
     
  4. Diabetes: women with diabetes are more likely to have hormonal imbalance issues.


Treatment of Endometrial Hyperplasia

The treatment of endometrial hyperplasia depends on its type and the degree of tissue proliferation.
The main treatment methods are as follows:

  • Hormone therapy: medications containing progesterone are used to balance estrogen levels and reduce endometrial proliferation.
     
  • Surgery: in some cases, it may be necessary to remove excess endometrial tissue or even remove the uterus (hysterectomy).
     
  • Monitoring and regular follow-up: mild forms of hyperplasia may only require regular follow-up with ultrasound and biopsy.

Endometrial Hyperplasia Before IVF


Before IVF, it is important to ensure optimal conditions for embryo implantation. Endometrial hyperplasia can hinder this process, so it is necessary to treat it before the procedure. The main steps of preparation are as follows:
Assessment of the endometrium: the doctor performs an ultrasound and, if necessary, a biopsy to evaluate the thickness and structure of the endometrium.
Hormonal preparation: hormonal treatment may be prescribed to reduce the proliferation of the endometrium and prepare the uterus for implantation. 
Regular monitoring of the endometrium.

IVF in Cases of Endometrial Hyperplasia
The IVF procedure in cases of endometrial hyperplasia requires a special approach and planning.
The basic steps are as follows:

  • The doctor establishes an individualized treatment plan, taking into account the patient's characteristics and the degree of endometrial hyperplasia.
     
  • A thorough preparation of the endometrium using hormonal therapy before embryo implantation.
     
  • Monitoring of the endometrium during the procedure.


Endometrial hyperplasia is a pathology that requires careful attention from specialists in terms of diagnosis and treatment, especially if the patient is considering IVF. Thanks to modern treatment methods and regular monitoring, a large percentage of women suffering from this condition can successfully undergo IVF and achieve the desired pregnancy.
 

Dr. Iñaki González-Foruria
Medical Director
COMB: 40780
Dr. Clàudia Forteza
Gynecologist in Human Assisted Reproduction
COMB: 50849
Dr. Rebeca Beguería
Gynecologist in Human Assisted Reproduction
COMB: 40754
Joan Massó
IVF Lab Director
CBC: 21270C
Dr. Manel Fabó
Anaesthetist Doctor
COMB 23569
Monica Mandas
Nursing
COIB: 057909
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