NatuVitro · Treatment Results

Your chances of getting pregnant, in clear numbers

Real NatuVitro results and the estimated probability of pregnancy over multiple transfers. We explain what each figure means.

View results for my situation

The work of an embryologist at the NatuVitro laboratory — Accurate data. Clear explanations.

IVF with own eggs and PGT · All age groups · 2025 data

1 transfer: 70.8%; Clinical result*
Up to 2 transfers: 91.5%; Mathematical model
Up to 3 transfers: 97.5%; Mathematical model

* Clinical pregnancy in patients who proceeded to embryo transfer after PGT. It is not equivalent to the birth of a child.

Values for two and three transfers are calculated using a model of identical and independent probabilities: 1 − (1 − p)ⁿ. These are not observed outcomes of repeated transfers and are not an individual prognosis. The model assumes that all transfers are available and does not account for changes in the chances during treatment.

Find out the results for your situation

Select a treatment program, age group, and PGT option. Compare the clinical rate per procedure with the estimated probability of pregnancy over several attempts.

There is no data for the selected combination. Probability calculation is unavailable.

Clinical pregnancy: baseline indicator Calculated probability: mathematical model

Find out the results for your situation

Clinical pregnancy: baseline indicator	The observed cumulative frequency over 2–3 attempts is not represented in these data.	The observed cumulative frequency over 2–3 attempts is not represented in these data.
Calculated probability: mathematical model

— The observed cumulative frequency over 2–3 attempts is not represented in these data.

Calculation: P(n) = 1 − (1 − p)ⁿ, where p is the initial probability of clinical pregnancy per procedure and n is the number of attempts. The model assumes equal, independent chances and that all attempts are available. Values for two and three attempts are not observed cumulative clinic statistics or an individual prediction.

Clinical pregnancy is confirmed by ultrasound and is not equivalent to the birth of a child. Results in the graph are rounded to one decimal place; the calculation uses the original value without intermediate rounding.

IVF with your own eggsAll age groupsWith PGT2025

The result applies to patients who proceeded to embryo transfer after PGT. It does not show the likelihood of obtaining an embryo suitable for transfer. Age-related differences in outcomes also depend on the composition and size of the groups.

IVF with own eggsAll age groupsWithout PGT2025

Clinic data for 2025. The metric refers to clinical pregnancy following embryo transfer, not the outcome of a complete IVF cycle.

IVF with own eggsUp to and including age 35With PGT2025

The result applies to patients who proceeded to embryo transfer after PGT. It does not indicate the probability of obtaining an embryo suitable for transfer. Age-related differences in outcomes also depend on the composition and size of the groups.

IVF WITH OWN EGGSUp to and including 35 years of ageWithout PGT2025

Clinic data for 2025. The indicator refers to clinical pregnancy after embryo transfer, not the outcome of a complete IVF cycle.

IVF with own eggs36–40 years oldWith PGT2025

The result applies to patients who proceeded to embryo transfer after PGT. It does not show the probability of obtaining an embryo suitable for transfer. Age-related differences in results also depend on the composition and size of the groups.

IVF with own eggs36–40 yearsWithout PGT2025

Clinic data for 2025. This figure refers to clinical pregnancy after embryo transfer, not the outcome of a complete IVF cycle.

IVF with own eggsOver 40 years oldWith PGT2025

The result applies to patients who proceeded to embryo transfer after PGT. It does not indicate the likelihood of obtaining an embryo suitable for transfer. Differences in outcomes by age also depend on the composition and size of the groups.

IVF with own eggsOver 40 years oldWithout PGT2025

In 2025, all patients in this age group underwent PGT. There are no data on transfers without PGT in this group; the lack of observations does not mean that the probability of pregnancy is zero.

IVF with donor eggsAll age groupsWith PGT2025

In the data provided, egg donation outcomes are combined across all age groups. No separate age breakdown is provided.

IVF with donor eggsAll age groupsWithout PGT2025

In the data provided, the results of egg donation are combined across all age groups. No separate age breakdown is provided.

Insemination with the partner's spermAll age groupsNot applicable2024–2025

Insemination results are reported for 2024–2025, without an age breakdown. One attempt here means one insemination, not an embryo transfer.

Insemination with donor spermAll age groupsNot applicable2024–2025

Insemination results are reported for 2024–2025, with no age breakdown. One attempt here means one insemination, not an embryo transfer.

What does treatment success mean?

Treatment outcomes are measured using different indicators. They describe different stages — from a positive test to the birth of a child. Understanding these differences helps you compare the figures correctly.

Positive test (β-hCG)

The blood test shows signs of pregnancy. A positive result does not yet confirm that it will continue to develop.
Clinical pregnancy

An ultrasound has confirmed the presence of a gestational sac. This is the indicator used to calculate the probability on this page.
Ongoing pregnancy

The pregnancy continues to develop. Its progress will be assessed by the doctor during follow-up.
Birth of a child

Live birth is the outcome that matters most to patients. Its rate is a separate measure and is not the same as the clinical pregnancy rate.

The data provided by NatuVitro report positive β-hCG and clinical pregnancy. Complete live birth statistics are not provided in these materials, so the published clinical pregnancy rate should not be considered the probability of having a baby.

Real results of NatuVitro

Select a program and compare two actual outcomes: a positive β-hCG test and a clinical pregnancy. Data for IVF is from 2025, while data for insemination is from 2024–2025.

Positive β-hCGClinical pregnancy

IVF with own eggs · With PGT

Up to and including 35 years old

β-hCG78.20%

CPR70.90%

—

The sample size has not been published.

The results apply to patients who proceeded to embryo transfer after PGT. They do not show the likelihood of obtaining an embryo suitable for transfer. Differences between age groups also depend on the composition and size of the samples.

IVF with own eggs · With PGT

36–40 years

2025

β-hCG74.30%

CPR67.60%

—

The sample size has not been published.

The results apply to patients who underwent embryo transfer after PGT. They do not indicate the likelihood of obtaining an embryo suitable for transfer. Differences between age groups also depend on the composition and size of the samples.

IVF with own eggs · With PGT

Over 40 years old

2025

β-hCG82.90%

CPR80.00%

—

The sample size has not been published.

IVF with own eggs · With PGT

All age groups

2025

β-hCG76.90%

CPR70.80%

—

The sample size has not been published.

The results apply to patients who proceeded to embryo transfer after PGT. They do not show the probability of obtaining an embryo suitable for transfer. Differences between age groups also depend on the composition and size of the samples.

IVF with own eggs · Without PGT

Up to and including 35 years of age

2025

β-hCG79.40%

CPR65.10%

—

The sample size has not been published.

2025 data for IVF using own eggs without PGT. There are no observations without PGT for the over-40 age group: all patients in this age group underwent genetic testing.

IVF with own eggs · No PGT

36–40 years

2025

β-hCG52.50%

CPR50.00%

—

The sample size has not been published.

2025 data for IVF using own eggs without PGT. There are no observations without PGT in the over-40 age group: all patients in this age group underwent genetic testing.

IVF with own eggs · No PGT

Over 40 years old

2025

β-hCG0.00%

CPR0.00%

—

No observations.

2025 data for IVF using own eggs without PGT. There are no observations without PGT for the over-40 age group: all patients in this age group underwent genetic testing.

IVF with own eggs · No PGT

All age groups

2025

β-hCG73.70%

CPR60.00%

—

The sample size has not been published.

2025 data for IVF using own eggs without PGT. There are no observations without PGT for the over-40 age group: all patients in this age group underwent genetic testing.

IVF with donor eggs · With PGT

All age groups

2025

β-hCG67.70%

CPR57.60%

—

The sample size has not been published.

The results of egg donation are presented for all age groups combined. These data do not include a separate age breakdown.

IVF with donor eggs · No PGT

All age groups

2025

β-hCG63.90%

CPR54.60%

—

The sample size has not been published.

The results of egg donation are presented for all age groups combined. A separate age breakdown is not provided in these data.

Insemination with partner’s sperm

All age groups

2024–2025

β-hCG18.20%

CPR13.60%

—

The sample size has not been published.

Actual results of a single insemination for 2024–2025. Age groups are not separated in these materials.

Donor sperm insemination

All age groups

2024–2025

β-hCG21.80%

CPR19.20%

—

The sample size has not been published.

Actual results of a single insemination for 2024–2025. Age groups are not separated in these materials.

A positive β-hCG is a positive blood test for pregnancy. Clinical pregnancy is confirmed by ultrasound. These outcomes are not equivalent to live birth.

The actual results are shown here, without calculating the probability over several attempts. Percentages refer to the outcome of an embryo transfer or insemination, not a full treatment cycle. A valid comparison requires consistent outcome definitions and denominators, as well as a verified number of procedures in each group.

How to compare clinic results?

Two percent in an advertisement can refer to different outcomes. Before comparing figures, clarify what counts as success, which stage of treatment the figure applies to, and which patients are included in the group.

For one transfer

Result of a single embryo transfer procedure. For comparison, it is important to know whether only first transfers or all transfers are counted, and which outcome is measured: a positive test, clinical pregnancy, or live birth.

Accumulated over one cycle

Takes into account the outcome of all embryo transfers resulting from a single egg retrieval or a single donor egg retrieval. One cycle may include several transfers, so its outcome differs from the outcome of a single transfer.

Accumulated over several cycles

Takes into account several complete treatment cycles and the transfers associated with them. Such results can be compared only when the number of cycles is the same, the groups are comparable, and success is defined in the same way.

Calculated probability

Calculated using a mathematical model based on the initial probability and specified assumptions. It should be distinguished from the observed cumulative pregnancy rate and assessed in light of the calculation conditions.

NatuVitro results and national statistics for Spain

The national SEF registry helps assess the context of the results. Before comparing them, it is important to check exactly what is being counted, over what period, and for which group of patients.

IVF with own eggs · With PGT

Direct comparison is not available yet.

NatuVitro

70.80%No confirmed data

2025 · All age groups
Clinical pregnancy after transfer.
Sample size not published.

Spain · SEF

0.00%Comparable metric not selected.

This program requires an indicator with the same type of transfer, PGT, and denominator.

The clinic’s materials describe the denominator inconsistently: as either the first transfer or transfers overall. Until this is clarified, we will not insert the national percentage. The overall SEF rate for all PGT programs cannot automatically be compared with the individual NatuVitro program.

IVF with own eggs · No PGT

Direct comparison is not yet available

NatuVitro

60.00%No confirmed data

2025 · All age groups
Clinical pregnancy after transfer.
Sample size not published.

Spain · SEF

0.00%No comparable indicator selected.

Comparable indicator not selected.

The clinic’s materials describe the denominator inconsistently: as either the first transfer or all transfers. Until this is clarified, we do not use the national percentage. The aggregate SEF rate for all PGT programs cannot be directly compared with the separate NatuVitro program.

IVF with donor eggs · With PGT

Direct comparison is not yet available.

NatuVitro

57.60%No confirmed data

2025 · All age groups
Clinical pregnancy after transfer.
Sample size not published.

Spain · SEF

0.00%No comparable indicator selected.

This program requires an indicator with the same transfer type, PGT, and denominator.

The clinic’s materials describe the denominator inconsistently: either the first transfer or transfers overall. Until this is clarified, we will not substitute the national percentage. The aggregate SEF figure for all PGT programs cannot automatically be compared with the separate NatuVitro program.

IVF with donor eggs · No PGT

Direct comparison is not available yet

NatuVitro

54.60%No confirmed data

2025 · All age groups
Clinical pregnancy after transfer.
Sample size not published.

Spain · SEF

0.00%No comparable indicator selected.

This program requires a metric with the same transfer type, PGT, and denominator.

The clinic materials describe the denominator inconsistently: as either the first transfer or transfers overall. Until this is clarified, we will not substitute the national percentage. The overall SEF figure for all PGT programs cannot be automatically compared with the individual NatuVitro program.

Insemination with the partner’s sperm

Different periods · Historical reference

NatuVitro

13.60%No confirmed data

2024–2025 · All age groups
Clinical pregnancy after insemination.
Sample size not published.

Spain · SEF

13.20%No confirmed data.

2023 · All age groups
Pregnancy per insemination cycle.
N = 15,696 cycles · Section 4.1, p. 61.

The periods differ: 2024–2025 and 2023. National data serve as a historical reference, not as evidence of the clinic’s superiority. A direct comparison also requires confirming that the clinical pregnancy criterion and unit of measurement are the same, and that the patient populations are comparable.

Donor sperm insemination

Different periods · Historical reference

NatuVitro

19.20%No confirmed data.

2024–2025 · All age groups
Clinical pregnancy after insemination.
Sample size not published.

Spain · SEF

18.50%

2023 · All age groups
Pregnancy per insemination cycle.
N = 14,768 cycles · Section 4.2, p. 62.

The periods differ: 2024–2025 and 2023. National data serve as a historical benchmark, not as evidence that the clinic is superior. A direct comparison also requires confirming that the clinical pregnancy criterion and unit of measurement are the same, and that the patient populations are comparable.

This is not a clinic ranking. A direct comparison requires the same outcomes, denominators, time periods, and comparable groups of patients. Data from different years are provided as a historical reference. Even when these conditions match, differences in patient composition and sample sizes remain.

Age groups also differ: NatuVitro — ≤35, 36–40, >40; SEF — <35, 35–39, ≥40. These groups cannot be compared directly. All age groups are shown together here.

National source: National Activity Registry 2023—SEF Registry (PDF), sections 4.1 and 4.2, pages 61–62. Clinic: RG-OPE-005, IVF results for 2025 and insemination results for 2024–2025.

Why does age matter?

In IVF using your own eggs, it is important to distinguish between two stages: obtaining an embryo for transfer and the outcome of a transfer that has already been performed. NatuVitro’s laboratory data show how the groups differ by age.

NatuVitro · 2025 · IVF with own eggs

Suitable blastocysts

Proportion of blastocysts transferred or frozen out of the number of normally fertilized eggs (2PN). This metric combines programs with and without PGT.

Euploidy in PGT

The proportion of blastocysts with a euploid result among blastocysts tested by PGT. A euploid result means a normal number of chromosomes according to the results of this test.

Suitable blastocystsEuploidy in PGT

Under 35 years old*

57.40%—

61.80%—

36–40 years old

49.80%—

47.70%—

Over 40 years old

35.00%—

14.70%—

The summary does not specify the number of fertilized eggs and blastocysts examined by age group.

The age boundaries are given as in the laboratory source: <35, 36–40, and >40 years. Age 35 is not explicitly assigned to a group; this should be clarified with the laboratory. Do not combine these groups with the clinical breakdown of ≤35, 36–40, and >40 without confirmation.

These are observed laboratory proportions for 2025. They have different denominators; multiplying the two charts does not yield the probability of pregnancy or childbirth. The sizes of the corresponding samples are not provided in the summary.

Source: DI-LAB-002 “Resumen tasas de laboratorio y clínicas”, rev.01 dated 30.03.2026: definitions — p. 1, age-related indicators — pp. 3 and 6. Verification: Anexo I de DI-LAB-002, pp. 16–18. IVF data using patients’ own eggs for 2025.

Dr. Cristina Pérez

Specialist in Assisted Reproduction
Medical Director

Dr. Jean-Paul Bouiller

Specialist in Assisted Reproduction

Dr. Frédéric Lamazou

Specialist in Assisted Reproduction

Dr. Karinna Lattes

Chief Scientific Officer

Dr. Elena Prada

Specialist in Assisted Reproduction

Dr. Maria Jesús Puy

Specialist in Assisted Reproduction

Dr. Patricia Zabala Franco

Specialist in Assisted Reproduction

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Your chances of getting pregnant, in clear numbers

Positive test (β-hCG)

Clinical pregnancy

Ongoing pregnancy

Birth of a child

IVF with own eggs · With PGT

Up to and including 35 years old

IVF with own eggs · With PGT

36–40 years

IVF with own eggs · With PGT

Over 40 years old

IVF with own eggs · With PGT

All age groups

IVF with own eggs · Without PGT

Up to and including 35 years of age

IVF with own eggs · No PGT

36–40 years

IVF with own eggs · No PGT

Over 40 years old

IVF with own eggs · No PGT

All age groups

IVF with donor eggs · With PGT

All age groups

IVF with donor eggs · No PGT

All age groups

Insemination with partner’s sperm

All age groups

Donor sperm insemination

All age groups

For one transfer

Accumulated over one cycle

Accumulated over several cycles

Calculated probability

NatuVitro

Spain · SEF

NatuVitro

Spain · SEF

NatuVitro

Spain · SEF

NatuVitro

Spain · SEF

NatuVitro

Spain · SEF

NatuVitro

Spain · SEF

Suitable blastocysts

Euploidy in PGT

Under 35 years old*

36–40 years old

Over 40 years old

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