Prof. Arsène Mekinian

Get a specialised reproductive immunology consultation

One of France's leading experts in reproductive immunology, recurrent implantation failure and pregnancy-related autoimmune disorders.

Almost fully booked — only September 10 and 11 are still open. Book your online consultation before it's gone.

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Why didn't my embryo implant?

An unsuccessful embryo transfer can be difficult to understand, especially when the embryo appeared suitable for transfer and no clear explanation has been found.

In some patients, immune, inflammatory or autoimmune factors may be worth investigating before another IVF attempt.

Discuss your case

Suspected autoimmune or inflammatory conditions

No clear explanation after the standard fertility work-up

Could the immune system play a role in implantation?

Embryo

Endometrium

Maternal immune system

Successful implantation requires complex interaction between the embryo, the endometrium and the maternal immune system.

In selected patients, Prof. Mekinian investigates whether immune or inflammatory mechanisms could be associated with implantation failure.

Areas of expertise include:

Endometrial immune response

Cytokines and inflammatory pathways

TNF-alpha

NK cells and the endometrial immune environment

Autoimmune factors

Antiphospholipid syndrome

Immunological factors associated with implantation failure

Immunomodulatory approaches when medically indicated

Consult one of France’s leading specialists in reproductive immunology

Reproductive immunology

Prof. Arsène Mekinian

Professor of Internal Medicine — Sorbonne University
Hôpital Saint-Antoine, AP-HP, Paris
Specialist in autoimmunity, pregnancy and reproductive immunology
Researcher in recurrent implantation failure
Researcher in recurrent unexplained miscarriage
Principal investigator and coordinator of major clinical research programmes in reproductive immunology
Author and co-author of hundreds of scientific publications

His clinical and research work focuses on understanding why implantation or pregnancy can fail when conventional investigations do not provide a clear explanation.

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Research directly connected to implantation failure

Current clinical research explores new approaches to recurrent implantation failure.

Recurrent implantation failure

Research into unexplained failure of embryo implantation after IVF.

Maternal immune response

Investigation of immune mechanisms involved in embryo–endometrium interaction.

TNF-alpha and inflammatory pathways

Clinical research into inflammatory mechanisms that may affect implantation.

Immunomodulation

Research into treatments that modify immune activity in carefully selected patients.

Autoimmunity

Identification of autoimmune conditions potentially relevant to fertility and pregnancy.

View selected scientific publications

Is this consultation appropriate for you?

This consultation may be particularly relevant if one or more of the following situations apply to you.

Book an appointment

You have experienced an unsuccessful embryo transfer

And want to understand whether further investigation may be useful.

You have experienced several implantation failures

Despite apparently favourable IVF conditions.

No clear explanation has been found

After your standard fertility assessment.

You have an autoimmune condition

Or previous tests have suggested an immune or inflammatory abnormality.

You want an expert second opinion

Before undergoing another IVF cycle or embryo transfer.

A specialised review of your IVF history

Review of your medical history

Your previous IVF cycles, embryo transfers, pregnancy history and relevant medical information are reviewed.

Assessment of possible immunological factors

Your history is assessed to determine whether additional immune or autoimmune investigation could be useful.

Additional investigations if appropriate

Further tests may be recommended depending on your individual situation.

Personalised medical recommendations

You receive recommendations to consider before your next IVF attempt or embryo transfer.

Book your consultation

Make the most of your consultation

Before your appointment, you can provide the following documents and information.

Previous IVF reports

Embryology reports

Embryo transfer reports

Previous blood tests

Autoimmune and immunological test results

Pregnancy and miscarriage history

Current medications

Relevant medical records

Consultation online without travelling

The consultation is conducted online in French, allowing patients anywhere in France to obtain specialist advice without travelling to Barcelona or Paris.

Medical records reviewed remotely

Consultation from home

In French

No travel required

Recommendations before your next IVF or embryo transfer

Coordinated with your fertility treatment when appropriate

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Limited consultation availability

Consultations for NatuVitro patients are offered through a limited number of appointment slots.

2 days are still open

Request your consultation and our French-speaking team will contact you to confirm the next available appointment.

Book your consultation

Before your next embryo transfer, get a specialist opinion

If your embryo did not implant and you still do not have a clear explanation, your history can be reviewed to determine whether an immunological assessment may be relevant to your case.

Online consultation in French

Limited appointments » only September 10 and 11 are still open

Request a consultation

First name * Last name * Email * Phone *

Number of previous IVF cycles Number of failed embryo transfers Previous miscarriages (optional)

I have medical reports available *

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It takes approximately 15 minutes to request an appointment

What people say about our services

100% real reviews about our care and services

5.0

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Marine J.

15/03/2024

Merci à toute l'équipe NatuVitro ! Le suivi humain, personnalisé et bienveillant nous a donné confiance en vous et en nous pour mener à bien notre projet PMA. Sur place, c'est avec un accueil chaleureux que nous avons été reçues puis prises en charge avec professionnalisme et bienveillance. Nous gardons un souvenir très positif de notre expérience avec vous. Merci.

Françoise B.

22/01/2024

Mon mari et moi avons choisis Natuvitro car possibilité de faire des transferts sur cycle naturel. Nous avons toujours réponses à nos questions et ce rapidement( merci Sabrina). Je suis suivie par le Docteur Begueria ( FIV DO). J'ai eu un premier transfert en novembre qui malheureusement c'est terminé en fausse couche...

Alessandra C.

17/01/2024

Je tiens à remercier le Docteur Gonzalez et toute l’équipe de Natuvitro pour leur accueil et leur professionnalisme. Je recommande vivement cette clinique car ils sont à l’écoute, bienveillants, ils sont très humain et disponible. Grâce au Docteur Gonzalez nous avons pu réaliser notre rêve 🤰🏼 Merci du fond du cœur

Jeremy R.

27/12/2023

J’ai eu la grande chance de tomber sur Natuvitro un peu par hasard car je cherchais une clinique de fertilité qui prônait plutôt une vision naturelle de la PMA, par exemple de pouvoir faire un transfert sur cycle naturel lorsque c’était possible. J’ai 43 ans et j’avais essuyé 5 échecs en insémination auparavant en France...

Tiffany T.

23/12/2023

1er essai concluant pour cette clinique qui bat des records de vitesse en insémination. Quasiment aucun délai à prévoir et une équipe à l'écoute et surtout du personnel très disponible. Contact par visio et échanges emails fructueux, nous recommandons vivement. Une partie de l'équipe est également bilingue français donc n'hésitez pas ! Zoé & Tiff

Monsieur F.

21/11/2023

Bonjour! Pour nous, NATUVITRO est la meilleure expérience de nos vies. Nous avions connu cette clinique par l’intermédiaire d’un homologue au Docteur Gonzalez, le Professeur Pietro Santulli que nous saluons de passage. Après 8ans d’attente, et avec le soutien inlassable d’un personnel toujours dévoué, gentil, compétent et professionnel...

Mariane D.

17/11/2023

Merci à toute l'équipe Natuvitro, et particulièrement à Sabrina et au Dr Begueria pour votre accueil chaleureux et votre écoute attentive. Relationnel très humain et suivi impeccable 🙂

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We are located in the heart of Barcelona.

Location

Travessera de les Corts, 322
08029 Barcelona Spain
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9:00 - 17:00, Mon - Fri

(+34) 936 555 888

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info@natuvitro.com

Photo inside of Natuvitro Clinic in Barcelona