The role of histology in gynecology

What is the histology of the uterine biopsy sample?

The histology of the uterine biopsy specimen is a diagnostic method that allows for the precise determination of the presence of a pathological process. This method aims to analyze the cellular composition of tissues, which allows for the identification of any changes and the establishment of a diagnosis. Histological examination is prescribed in cases of suspicion of disease, as it enables accurate diagnosis of the pathological process.

When is histology performed in gynecology?

The gynecologist requests a histological examination in cases of suspected pathological processes at the level of the cervix. For example, if suspicious changes in the cellular composition of tissues are detected. Cervical histology is prescribed in the following cases:

• Suspicious results from a cytological smear;
• Presence of cervical polyps;
• Suspicious results from a colposcopy;
• Presence of cervical erosion or dysplasia;
• Detection of condylomas;
• Suspicion of oncological processes and other pathologies.

What does histology show?

The material obtained during the biopsy is sent to the laboratory for macro- and microscopic examination. Specialists analyze the tissue, identify potential changes, and provide their results. If the histological examination reveals no cellular changes, it is interpreted as normal. If pathologies are detected, the changes can take various forms, including:

• Endometrial hyperplasia;
• Atrophic changes in the tissue;
• Fibrosis of the mucosa;
• Presence of cysts;
• Mucosal infiltration;
• Proliferation of the epithelium;
• Presence of apoptotic cells;
• Inflammation of endometrial cells, and others.

The nature of the pathological changes in the tissue sample allows the physician to determine the type of disease and make an accurate diagnosis. Several factors can affect the result of a histological examination, including the phase of the menstrual cycle during which the biopsy was performed, the volume of material obtained, and the experience of the physician performing the procedure, such as a diagnostic curettage or a colposcopic biopsy.

How is the material for cervical histology collected?

Tissue sampling for histological examination can be done in different ways. Tissue can be obtained by scraping the walls of the cervical canal and the uterine cavity or by aspiration biopsy. Separate scraping may be prescribed for both diagnostic and therapeutic purposes, for example, to remove a polyp or stop bleeding. During the procedure, the physician collects epithelial cells from the inner surface of the uterus and cervix, and the obtained material is sent to the laboratory for analysis.

Tissues intended for histological examination of the cervix and the uterus itself can also be collected during colposcopy. Colposcopy is a procedure during which the physician examines the vagina and the uterine cavity using a special optical device called a colposcope. During the examination, the physician can detect suspicious areas and take a tissue sample from these areas using a special instrument. This allows for the precise determination of the presence of a pathology and its nature.

Consultation and diagnosis

If you need a histological examination of uterine tissue or wish to consult the results of the diagnosis, you can contact a gynecologist-obstetrician at the NatuVitro clinic. The clinic also offers examinations for pregnancy planning, as well as diagnostics for couples who have difficulties conceiving a child. The specialists at the clinic will help you obtain advice and plan an in vitro fertilization (IVF), including IVF with egg donation and IVF with double donation.

The NatuVitro clinic offers a comprehensive range of services for the diagnosis and treatment of reproductive issues, from the initial examination to high-tech procedures such as IVF. All examinations and procedures are performed using modern equipment and the latest techniques, ensuring the accuracy of the diagnosis and the effectiveness of the treatment.

By turning to "NatuVitro," you can be assured of receiving highly qualified medical assistance and support at every step of the treatment. The specialists at the clinic provide medical and psychological support, helping you achieve the desired result - the conception and birth of a healthy child.